Epithalon & Pinealon Blend – 30mg/15mg (45mg Total) | Research Compound

This blend combines two of the most studied Khavinson bioregulator peptides — Epithalon, which supports telomerase activation and longevity, and Pinealon, which enhances cognitive function and neural protection. Both peptides were developed at the St. Petersburg Institute of Bioregulation and Gerontology under the guidance of Professor Vladimir Khavinson, and both originate from research into pineal gland-derived signaling molecules, making this combination a natural pairing for researchers studying pineal-linked systemic and neurological pathways together.

Mechanism & Research Rationale:

Epithalon was originally derived from the pineal gland and is known for its ability to activate telomerase and protect chromosomes during replication, extending cellular lifespan, with research also examining its role in antioxidant defense and circadian/melatonin regulation. Pinealon, by contrast, is more focused on neurological function, having been studied for its potential to regulate gene expression in neurons, supporting cognitive performance, brain cell protection, and overall neural health. Mechanistically, Pinealon is hypothesized to be capable of crossing lipid bilayers, including the cell and nuclear membranes, thereby enabling direct interaction with DNA — a mechanism shared conceptually with Epithalon’s own proposed gene-regulatory action, giving researchers two complementary tools for studying pineal-linked, DNA-interactive peptide bioregulation side by side.

Key Research Areas:

• Telomerase & Cellular Aging (Epithalon) — Epithalon is being actively researched to explore the mechanisms by which this peptide may mediate longevity through telomerase activation and reduction of oxidative damage.
• Neuronal Gene Expression & Cognitive Research (Pinealon) — Proposed biological mechanisms for Pinealon include regulation of mRNA expression associated with neuronal repair and suppression of oxidative stress and free radical damage.
• Circadian & Sleep-Wake Cycle Research — Both peptides converge on circadian-related research; Pinealon has been observed in early research to play a potential role in modulating the sleep-wake cycle and associated physiological behaviors.
• Comparative Pineal-Bioregulator Research — Because both peptides originate from pineal gland-derived research and share overlapping (but distinct) DNA-interactive mechanisms, they are frequently studied together to differentiate systemic/telomere-focused effects (Epithalon) from neuron-specific effects (Pinealon).

Product Specifications:

• Epithalon: 30mg | Sequence: Ala-Glu-Asp-Gly (AEDG)
• Pinealon: 15mg | Sequence: Glu-Asp-Arg (EDR)
• 45mg total lyophilized powder per vial
• ≥99% purity via HPLC, third-party COA available
• Store refrigerated (2–8°C) or frozen for long-term storage; protect from light and moisture

For laboratory and research use only. Not intended for human or animal consumption, diagnostic, or therapeutic use. Not a drug, dietary supplement, or cosmetic. Not FDA-approved.